Polymicrobial infection in campylobacter enteritis.

showed a haemoglobin concentration of 124 g 1; white cell count 2-4x 109/1 (76°,' neutrophils, 20",, lymphocytes, 4",, monocvtes); platelet count 200 x 109 1; sedimentation rate 44 mm in first hour; normal urea and electrolytes and liver function values; antinuclear factor titre positive at 1/1280; rheumatoid arthritis haemagglutination titre positive at 1 80; and double stranded deoxyribonucleic acid (DNA) binding 94 U ml (normal 25 U'ml). She was a slow acetylator and her HLA type was Al AW24 B7 B17 DR2, DR3. Chest x ray appearances were normal. In view of the polvarthritis, cutaneous vasculitis, pleurisy, leucopenia, positive antinuclear factor titre, and raised DNA binding value, a diagnosis of carbamazepine induced systemic lupus erythematosus was made. The carbamazepine was withdrawn but the phenobarbitone continued. Predisolone 30 mg daily was added. The patient improved rapidly and prednisolone was stopped after six months. Subsequently she remained well for 12 months. The DNA binding returned to normal but her antinuclear factor titre remained positive at 1160.